3OTX
Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Inhibitor AP5A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Adenosine kinase, putative | polymer | 347 | 38131.5 | 2 | UniProt (Q584S0) Pfam (PF00294) | Trypanosoma brucei | |
| 2 | C, E (A, B) | BIS(ADENOSINE)-5'-PENTAPHOSPHATE | non-polymer | 916.4 | 2 | Chemie (AP5) | |||
| 3 | D, F (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 626 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 345 (UniProt: Q584S0)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 2 | Ser 2 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76263.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1878.7 | |
| All* | Total formula weight | 78141.7 |
