3OS9

Estrogen Receptor

Summary for 3OS9

Entry DOI	10.2210/pdb3os9/pdb
Related	3OS8 3OSA
Descriptor	Estrogen receptor, 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol (3 entities in total)
Functional Keywords	estrogen receptor complex, signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	120536.76
Authors	Bruning, J.,Parent, A.A.,Gil, G.,Zhao, M.,Nowak, J.,Pace, M.C.,Smith, C.L.,Afonine, P.V.,Adams, P.D.,Katzenellenbogen, J.A.,Nettles, K.W. (deposition date: 2010-09-08, release date: 2010-11-10, Last modification date: 2024-02-21)
Primary citation	Bruning, J.B.,Parent, A.A.,Gil, G.,Zhao, M.,Nowak, J.,Pace, M.C.,Smith, C.L.,Afonine, P.V.,Adams, P.D.,Katzenellenbogen, J.A.,Nettles, K.W. Coupling of receptor conformation and ligand orientation determine graded activity. Nat.Chem.Biol., 6:837-843, 2010 Cited by PubMed: 20924370 DOI: 10.1038/nchembio.451 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.303 Å)

Structure validation