3OS8
Estrogen Receptor
Summary for 3OS8
Entry DOI | 10.2210/pdb3os8/pdb |
Related | 3OS9 3OSA |
Descriptor | Estrogen receptor, 4-[1-benzyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol, ... (4 entities in total) |
Functional Keywords | estrogen receptor complex, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform 1: Nucleus. Isoform 3: Nucleus: P03372 P03372 |
Total number of polymer chains | 4 |
Total formula weight | 119552.06 |
Authors | Bruning, J.,Parent, A.A.,Gil, G.,Zhao, M.,Nowak, J.,Pace, M.C.,Smith, C.L.,Afonine, P.V.,Adams, P.D.,Katzenellenbogen, J.A.,Nettles, K.W. (deposition date: 2010-09-08, release date: 2010-11-10, Last modification date: 2021-10-06) |
Primary citation | Bruning, J.B.,Parent, A.A.,Gil, G.,Zhao, M.,Nowak, J.,Pace, M.C.,Smith, C.L.,Afonine, P.V.,Adams, P.D.,Katzenellenbogen, J.A.,Nettles, K.W. Coupling of receptor conformation and ligand orientation determine graded activity. Nat.Chem.Biol., 6:837-843, 2010 Cited by PubMed: 20924370DOI: 10.1038/nchembio.451 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.031 Å) |
Structure validation
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