3OOI
Crystal Structure of Human Histone-Lysine N-methyltransferase NSD1 SET domain in Complex with S-adenosyl-L-methionine
Summary for 3OOI
Entry DOI | 10.2210/pdb3ooi/pdb |
Descriptor | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | set domain, histone-lysine n-methyltransferase, s-adenosyl-l-methionine, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q96L73 |
Total number of polymer chains | 1 |
Total formula weight | 27313.03 |
Authors | |
Primary citation | Qiao, Q.,Li, Y.,Chen, Z.,Wang, M.,Reinberg, D.,Xu, R.M. The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation J.Biol.Chem., 286:8361-8368, 2010 Cited by PubMed: 21196496DOI: 10.1074/jbc.M110.204115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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