3ONB

Bond breakage and relocation of a covalently bound bromine of IDD594 in a complex with hAR T113A mutant after extensive radiation dose

Summary for 3ONB

• Entry DOI: 10.2210/pdb3onb/pdb
• Related: 1US0 3LBO 3LD5 3LQL 3ONC
• Descriptor: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, IDD594, ... (6 entities in total)
• Functional Keywords: radiation damage, t113a mutant, tim barrel, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P15121
• Total number of polymer chains: 1
• Total formula weight: 37168.79

Authors

Koch, C.,Heine, A.,Klebe, G. (deposition date: 2010-08-28, release date: 2011-08-17, Last modification date: 2024-03-20)

• Primary citation: Koch, C.,Heine, A.,Klebe, G.; Radiation damage reveals promising interaction position; J.SYNCHROTRON RADIAT., 18:782-789, 2011; PubMed: 21862860; DOI: 10.1107/S0909049511027920

Experimental method

X-RAY DIFFRACTION (1.45 Å)