3OIG

Crystal Structure of Enoyl-ACP Reductases I (FabI) from B. subtilis (complex with NAD and INH)

Summary for 3OIG

Entry DOI	10.2210/pdb3oig/pdb
Related	3OIC 3OID 3OIF
Descriptor	Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (2E)-N-[(1,2-dimethyl-1H-indol-3-yl)methyl]-N-methyl-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)prop-2-enamide, ... (4 entities in total)
Functional Keywords	fatty acid synthesis, rossmann-like fold, enoyl-acp reductases, nadh binding, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Bacillus subtilis
Total number of polymer chains	1
Total formula weight	30028.77
Authors	Kim, K.-H.,Ha, B.H.,Kim, S.J.,Hong, S.K.,Hwang, K.Y.,Kim, E.E. (deposition date: 2010-08-19, release date: 2011-01-05, Last modification date: 2023-11-01)
Primary citation	Kim, K.-H.,Ha, B.H.,Kim, S.J.,Hong, S.K.,Hwang, K.Y.,Kim, E.E. Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis J.Mol.Biol., 406:403-415, 2011 Cited by PubMed: 21185310 DOI: 10.1016/j.jmb.2010.12.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation