3OIG

Crystal Structure of Enoyl-ACP Reductases I (FabI) from B. subtilis (complex with NAD and INH)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0030497	biological_process	fatty acid elongation
A	0070417	biological_process	cellular response to cold

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	BINDING SITE FOR RESIDUE NAD A 1501

Chain	Residue
A	GLY14
A	THR69
A	CYS94
A	ILE95
A	ALA96
A	LEU146
A	THR147
A	LYS165
A	ALA191
A	GLY192
A	PRO193
A	VAL15
A	ILE194
A	THR196
A	LEU197
A	SER198
A	HOH271
A	HOH274
A	HOH276
A	HOH282
A	IMJ301
A	HOH487
A	ALA16
A	HOH500
A	HOH501
A	SER20
A	ILE21
A	ALA41
A	CYS66
A	ASP67
A	VAL68

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE IMJ A 301

Chain	Residue
A	PHE97
A	ALA98
A	TYR148
A	ASN157
A	TYR158
A	SER198
A	ILE202
A	HOH299
A	HOH384
A	NAD1501

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21185310","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Site: {"description":"Involved in acyl-ACP binding","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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