3OBG

Conformational plasticity of p38 MAP kinase DFG mutants in response to inhibitor binding

Summary for 3OBG

• Entry DOI: 10.2210/pdb3obg/pdb
• Related: 3MGY 3MH0 3MH1 3MH2 3MH3 3O8P 3O8T 3O8U 3OBJ 3OC1
• Descriptor: Mitogen-activated protein kinase 14, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE (3 entities in total)
• Functional Keywords: transferase
• Biological source: Homo sapiens
• Cellular location: Cytoplasm (By similarity): Q16539
• Total number of polymer chains: 1
• Total formula weight: 41630.51

Authors

Namboodiri, H.V.,Karpusas, M.,Bukhtiyarova, M.,Springman, E.B. (deposition date: 2010-08-06, release date: 2010-08-25, Last modification date: 2023-09-06)

• Primary citation: Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J.; Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)