3O3R
Crystal Structure of AKR1B14 in complex with NADP
Summary for 3O3R
Entry DOI | 10.2210/pdb3o3r/pdb |
Descriptor | Aldo-keto reductase family 1, member B7, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | aldose reductase like protein, akr1b14, oxidoreductase |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 2 |
Total formula weight | 73834.33 |
Authors | Sundaram, K.,Dhagat, U.,El-Kabbani, O. (deposition date: 2010-07-26, release date: 2011-01-19, Last modification date: 2023-11-01) |
Primary citation | Sundaram, K.,Dhagat, U.,Endo, S.,Chung, R.,Matsunaga, T.,Hara, A.,El-Kabbani, O. Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis Bioorg.Med.Chem.Lett., 21:801-804, 2011 Cited by PubMed: 21168333DOI: 10.1016/j.bmcl.2010.11.086 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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