3O2X

MMP-13 in complex with selective tetrazole core inhibitor

Summary for 3O2X

• Entry DOI: 10.2210/pdb3o2x/pdb
• Related: 3KRY
• Descriptor: Collagenase 3, N-hydroxy-1-(2-methoxyethyl)-4-{[4-(3-{5-[4-(trifluoromethoxy)phenyl]-2H-tetrazol-2-yl}propoxy)phenyl]sulfonyl}piperidine-4-carboxamide, ZINC ION, ... (7 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix (Probable): P45452
• Total number of polymer chains: 4
• Total formula weight: 78374.00

Authors

Kiefer, J.R.,Barta, T.E.,Becker, D.P.,Mathis, K.J.,Williams, J. (deposition date: 2010-07-22, release date: 2011-08-10, Last modification date: 2024-02-21)

• Primary citation: Barta, T.E.,Becker, D.P.,Bedell, L.J.,Hockerman, S.L.,Kiefer, J.R.,Li, M.H.,Villamill, C.I.,Rico, J.G.,Mcdonald, J.J.; MMP-13 in complex with selective tetrazole core inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)