3NUN
phosphoinositide-dependent kinase-1 (PDK1) with lead compound
Summary for 3NUN
Entry DOI | 10.2210/pdb3nun/pdb |
Related | 3NUS 3NUU 3NUY |
Descriptor | PkB-like, GLYCEROL, SULFATE ION, ... (5 entities in total) |
Functional Keywords | kinase domain, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34956.83 |
Authors | Campobasso, N.,Ward, P. (deposition date: 2010-07-07, release date: 2011-06-22, Last modification date: 2011-07-13) |
Primary citation | Medina, J.R.,Blackledge, C.W.,Heerding, D.A.,Campobasso, N.,Ward, P.,Briand, J.,Wright, L.,Axten, J.M. Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery TO BE PUBLISHED, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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