3NUS
phosphoinositide-dependent kinase-1 (PDK1) with fragment8
Summary for 3NUS
Entry DOI | 10.2210/pdb3nus/pdb |
Related | 3NUN 3NUU 3NUY |
Descriptor | phosphoinositide-dependent kinase-1, GLYCEROL, 1H-indazol-3-amine, ... (5 entities in total) |
Functional Keywords | kinase domain, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 33897.47 |
Authors | Campobasso, N.,Ward, P. (deposition date: 2010-07-07, release date: 2011-05-25, Last modification date: 2018-10-10) |
Primary citation | Medina, J.R.,Blackledge, C.W.,Heerding, D.A.,Campobasso, N.,Ward, P.,Briand, J.,Wright, L.,Axten, J.M. Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery. ACS Med Chem Lett, 1:439-442, 2010 Cited by PubMed: 24900229DOI: 10.1021/ml100136n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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