3NUB

WbpE, an Aminotransferase from Pseudomonas aeruginosa Involved in O-antigen Assembly in Complex with Product as the External Aldimine

Summary for 3NUB

• Entry DOI: 10.2210/pdb3nub/pdb
• Related: 3NU7 3NU8
• Descriptor: Aminotransferase WbpE, (2S,3S,4R,5R,6R)-5-(acetylamino)-6-{[(S)-{[(S)-{[(2S,3R,4S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3-hydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}tetrahydro-2H-pyran-2-carboxylic acid, GLYCEROL, ... (5 entities in total)
• Functional Keywords: domain-swapped beta hairpin, aminotransferase, external aldimine, plp, pmp, udp-glcnac(3nh2)a, lipopolysaccharide, pseudomonas aeruginosa, o-antigen, b-band, transferase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 79818.21

Authors

Larkin, A.,Olivier, N.B.,Imperiali, B. (deposition date: 2010-07-06, release date: 2010-07-28, Last modification date: 2023-09-06)

• Primary citation: Larkin, A.,Olivier, N.B.,Imperiali, B.; Structural Analysis of WbpE from Pseudomonas aeruginosa PAO1: A Nucleotide Sugar Aminotransferase Involved in O-Antigen Assembly; Biochemistry, 49:7227-7237, 2010; PubMed: 20604544; DOI: 10.1021/bi100805b

Experimental method

X-RAY DIFFRACTION (1.9 Å)