3NSJ
The X-ray crystal structure of lymphocyte perforin
Summary for 3NSJ
Entry DOI | 10.2210/pdb3nsj/pdb |
Descriptor | Perforin-1, GLYCEROL, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | pore forming protein, immune system |
Biological source | Mus musculus (mouse) |
Cellular location | Cytoplasmic granule lumen: P10820 |
Total number of polymer chains | 1 |
Total formula weight | 61955.14 |
Authors | Law, R.H.,Whisstock, J.C.,Caradoc-Davies, T.T. (deposition date: 2010-07-01, release date: 2010-11-03, Last modification date: 2023-12-27) |
Primary citation | Law, R.H.,Lukoyanova, N.,Voskoboinik, I.,Caradoc-Davies, T.T.,Baran, K.,Dunstone, M.A.,D'Angelo, M.E.,Orlova, E.V.,Coulibaly, F.,Verschoor, S.,Browne, K.A.,Ciccone, A.,Kuiper, M.J.,Bird, P.I.,Trapani, J.A.,Saibil, H.R.,Whisstock, J.C. The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature, 468:447-451, 2010 Cited by PubMed: 21037563DOI: 10.1038/nature09518 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
Download full validation report