3NSJ
The X-ray crystal structure of lymphocyte perforin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Perforin-1 | polymer | 540 | 60799.0 | 1 | UniProt (P10820) Pfam (PF01823) Pfam (PF00168) | Mus musculus (mouse) | P1, Lymphocyte pore-forming protein, Cytolysin |
| 2 | B, C, D (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | E, F (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | G, H, I, J (A) | IODIDE ION | non-polymer | 126.9 | 4 | Chemie (IOD) | |||
| 5 | K, L (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | M (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | N (A) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A: 21 - 554 (UniProt: P10820)
| PDB | External Database | Details |
|---|---|---|
| Glu 213 | Arg 213 | engineered mutation |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| His 559 | - | expression tag |
| His 560 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60799.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1156.2 | |
| All* | Total formula weight | 61955.1 |
