3NQ6
Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP
Summary for 3NQ6
Entry DOI | 10.2210/pdb3nq6/pdb |
Related | 3G18 3NQ6 3NQ7 3NQA 3NQC 3NQD 3NQE 3NQF 3NQG 3NQM |
Descriptor | Orotidine 5'-phosphate decarboxylase, 6-AZA URIDINE 5'-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | orotidine 5'-monophosphate decarboxylase, methanobacterium thermoautotrophicum, inhibitor 6-azaump, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Methanothermobacter thermautotrophicus |
Total number of polymer chains | 2 |
Total formula weight | 50459.75 |
Authors | Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. (deposition date: 2010-06-29, release date: 2011-05-11, Last modification date: 2024-03-20) |
Primary citation | A Fedorov, A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP To be Published, |
Experimental method | X-RAY DIFFRACTION (1.494 Å) |
Structure validation
Download full validation report