3NL0
Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Summary for 3NL0
Entry DOI | 10.2210/pdb3nl0/pdb |
Related | 1u09 1WNE 2E9R 2E9T 2E9Z 2EC0 3NKY |
Descriptor | 3D polymerase, 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*G*GP*GP*CP*CP*C)-3', ... (5 entities in total) |
Functional Keywords | foot-and-mouth disease virus picornavirus, 3d polymerase, rna dependent rna polymerase, transferase-rna complex, transferase/rna |
Biological source | Foot-and-mouth disease virus - type C More |
Total number of polymer chains | 3 |
Total formula weight | 57429.61 |
Authors | Agudo, R.,Ferrer-Orta, C.,Arias, A.,Perez-Luque, R.,Verdaguer, N.,Domingo, E. (deposition date: 2010-06-21, release date: 2011-07-13, Last modification date: 2023-11-01) |
Primary citation | Agudo, R.,Ferrer-Orta, C.,Arias, A.,de la Higuera, I.,Perales, C.,Perez-Luque, R.,Verdaguer, N.,Domingo, E. A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6:e1001072-e1001072, 2010 Cited by PubMed: 20865120DOI: 10.1371/journal.ppat.1001072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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