3NL0
Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3D polymerase | polymer | 475 | 53262.4 | 1 | UniProt (Q9QCE4) Pfam (PF00680) | Foot-and-mouth disease virus - type C | |
| 2 | B (B) | 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3' | polymer | 7 | 2212.4 | 1 | |||
| 3 | C (C) | 5'-R(*G*GP*GP*CP*CP*C)-3' | polymer | 6 | 1906.2 | 1 | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F (A) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A: 1 - 470 (UniProt: Q9QCE4)
| PDB | External Database | Details |
|---|---|---|
| Ser 44 | Pro 1901 | engineered mutation |
| Ile 296 | Met 2153 | engineered mutation |
| Ala 471 | - | expression tag |
| Ala 472 | - | expression tag |
| Leu 473 | - | expression tag |
| Ala 474 | - | expression tag |
| His 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 57381.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 57429.6 |
