3NKB
A 1.9A crystal structure of the HDV ribozyme precleavage suggests both Lewis acid and general acid mechanisms contribute to phosphodiester cleavage
Summary for 3NKB
Entry DOI | 10.2210/pdb3nkb/pdb |
Related | 1CX0 1SJ3 |
Descriptor | DNA/RNA (5'-D(*(DUR))-D(*GP*G)-R(P*CP*UP*UP*GP*CP*A)-3'), The hepatitis delta virus ribozyme, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | catalytic rna, metal-mediated catalysis, phosphodiester cleavage, dna, rna |
Total number of polymer chains | 2 |
Total formula weight | 23636.17 |
Authors | Chen, J.-H.,Yajima, R.,Chadalavada, D.M.,Chase, E.,Bevilacqua, P.C.,Golden, B.L. (deposition date: 2010-06-18, release date: 2010-09-01, Last modification date: 2023-09-06) |
Primary citation | Chen, J.H.,Yajima, R.,Chadalavada, D.M.,Chase, E.,Bevilacqua, P.C.,Golden, B.L. A 1.9 A crystal structure of the HDV ribozyme precleavage suggests both Lewis acid and general acid mechanisms contribute to phosphodiester cleavage. Biochemistry, 49:6508-6518, 2010 Cited by PubMed: 20677830DOI: 10.1021/bi100670p PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.916 Å) |
Structure validation
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