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3NJQ

Crystal structure of Kaposi's sarcoma-associated herpesvirus protease in complex with dimer disruptor

Summary for 3NJQ
Entry DOI10.2210/pdb3njq/pdb
DescriptorORF 17, ACETATE ION, 3-benzyl-4-({[6-(cyclohexylmethyl)pyridin-2-yl]carbonyl}amino)benzoic acid, ... (7 entities in total)
Functional Keywordsprotein-dimer disruptor complex, kshv, kshv protease, herpesvirus protease, viral protein-inhibitor complex, viral protein/inhibitor
Biological sourceHuman herpesvirus 8 type M
More
Total number of polymer chains2
Total formula weight44159.12
Authors
Baharuddin, A. (deposition date: 2010-06-17, release date: 2011-08-17, Last modification date: 2017-11-08)
Primary citationLee, G.M.,Shahian, T.,Baharuddin, A.,Gable, J.E.,Craik, C.S.
Enzyme inhibition by allosteric capture of an inactive conformation.
J.Mol.Biol., 411:999-1016, 2011
Cited by
PubMed: 21723875
DOI: 10.1016/j.jmb.2011.06.032
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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