3NJP

The Extracellular and Transmembrane Domain Interfaces in Epidermal Growth Factor Receptor Signaling

3NJP の概要

• エントリーDOI: 10.2210/pdb3njp/pdb
• 分子名称: Epidermal growth factor receptor, Epidermal growth factor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: receptor tyrosine kinase, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 151812.47

構造登録者

Lu, C.,Mi, L.-Z.,Grey, M.J.,Zhu, J.,Graef, E.,Yokoyama, S.,Springer, T.A. (登録日: 2010-06-17, 公開日: 2010-10-13, 最終更新日: 2023-09-06)

• 主引用文献: Lu, C.,Mi, L.Z.,Grey, M.J.,Zhu, J.,Graef, E.,Yokoyama, S.,Springer, T.A.; Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor.; Mol.Cell.Biol., 30:5432-5443, 2010; PubMed: 20837704; DOI: 10.1128/MCB.00742-10

実験手法

X-RAY DIFFRACTION (3.304 Å)