3NDX

HIV-1 Protease Saquinavir:Ritonavir 1:50 complex structure

Summary for 3NDX

• Entry DOI: 10.2210/pdb3ndx/pdb
• Related PRD ID: PRD_001001
• Descriptor: Protease, RITONAVIR, DIMETHYL SULFOXIDE, ... (7 entities in total)
• Functional Keywords: hiv-1 protease, hydrolase, aids, aspartyl protease, saquinavir, carbamylation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 2
• Total formula weight: 22926.60

Authors

Geremia, S.,Olajuyigbe, F.M.,Demitri, N. (deposition date: 2010-06-08, release date: 2011-07-20, Last modification date: 2024-02-21)

• Primary citation: Olajuyigbe, F.M.,Demitri, N.,Geremia, S.; Investigation of 2-Fold Disorder of Inhibitors and Relative Potency by Crystallizations of HIV-1 Protease in Ritonavir and Saquinavir Mixtures; Cryst.Growth Des., 11:4378-4385, 2011; DOI: 10.1021/cg200514z

Experimental method

X-RAY DIFFRACTION (1.03 Å)