Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE RIT A 100 |
Chain | Residue |
A | ARG8 |
A | PRO81 |
A | HOH110 |
A | HOH164 |
A | HOH216 |
A | GOL1041 |
B | ASP25 |
B | GLY27 |
B | ALA28 |
B | ASP29 |
B | ILE47 |
A | ASP25 |
B | GLY48 |
B | GLY49 |
B | ILE50 |
B | VAL82 |
B | ILE84 |
B | HOH125 |
B | HOH221 |
A | GLY27 |
A | ALA28 |
A | ASP29 |
A | ASP30 |
A | GLY48 |
A | GLY49 |
A | ILE50 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE DMS A 991 |
Chain | Residue |
A | GLN92 |
A | HOH170 |
A | HOH210 |
B | GLY49 |
B | GLY52 |
B | PHE53 |
B | HOH171 |
site_id | AC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A 1041 |
Chain | Residue |
A | TRP6 |
A | GLY48 |
A | RIT100 |
A | HOH122 |
A | HOH145 |
A | HOH171 |
A | HOH277 |
B | PRO81 |
B | HOH123 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 308 |
Chain | Residue |
A | LYS7 |
A | ARG8 |
A | HOH305 |
B | HOH307 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 100 |
Chain | Residue |
B | PRO1 |
B | ARG57 |
B | HIS69 |
B | HOH138 |
B | HOH139 |
B | HOH284 |
site_id | AC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL B 101 |
Chain | Residue |
B | VAL11 |
B | THR12 |
B | TRP42 |
B | ALA67 |
B | HOH137 |
B | HOH176 |
B | HOH181 |
B | HOH342 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE DMS B 992 |
Chain | Residue |
A | GLY17 |
B | LYS14 |
B | ILE15 |
B | GLY16 |
B | GLY17 |
B | ILE63 |
B | GLU65 |
site_id | AC8 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE DMS B 993 |
Chain | Residue |
A | PRO39 |
A | GLY40 |
A | HOH142 |
A | HOH223 |
A | HOH323 |
B | MET36 |
B | SER37 |
B | HOH111 |
B | HOH172 |
site_id | AC9 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE DMS B 994 |
Chain | Residue |
A | LYS14 |
A | ILE15 |
A | GLY16 |
A | GLY17 |
A | ILE63 |
A | HOH271 |
B | LYS14 |
site_id | BC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 B 1040 |
Chain | Residue |
A | PRO1 |
A | LYS55 |
B | HIS69 |
B | LYS70 |
B | HOH170 |
B | HOH203 |
B | HOH237 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
Chain | Residue | Details |
A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP25 | |
B | ASP25 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | SITE: Cleavage; by viral protease => ECO:0000250 |
Chain | Residue | Details |
A | PHE99 | |
B | PHE99 | |