3N5S
Structure of endothelial nitric oxide synthase heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine
Summary for 3N5S
Entry DOI | 10.2210/pdb3n5s/pdb |
Related | 3N5P 3N5Q 3N5R 3N5T 3N5V 3N5W 3N5X 3N5Y 3N5Z 3N60 3N61 3N62 3N63 3N64 3N65 3N66 3N67 3N68 3N69 3N6A 3N6B 3N6C 3N6D 3N6E 3N6F 3N6G |
Descriptor | Nitric oxide synthase, PROTOPORPHYRIN IX CONTAINING FE, ACETATE ION, ... (9 entities in total) |
Functional Keywords | nitric oxide synthase, heme enzyme, substrate inhibitor, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Bos taurus (cow) |
Total number of polymer chains | 2 |
Total formula weight | 102474.27 |
Authors | Delker, S.L.,Li, H.,Poulos, T.L. (deposition date: 2010-05-25, release date: 2011-02-09, Last modification date: 2024-02-21) |
Primary citation | Delker, S.L.,Xue, F.,Li, H.,Jamal, J.,Silverman, R.B.,Poulos, T.L. Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase . Biochemistry, 49:10803-10810, 2010 Cited by PubMed: 21138269DOI: 10.1021/bi1013479 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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