3N5S
Structure of endothelial nitric oxide synthase heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nitric oxide synthase | polymer | 444 | 49710.1 | 2 | UniProt (P29473) Pfam (PF02898) In PDB | Bos taurus (cow) | Endothelial NOS, eNOS, EC-NOS, NOS type III, NOSIII, Constitutive NOS, cNOS |
2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
3 | A, B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | A, B | CACODYLIC ACID | non-polymer | 138.0 | 2 | Chemie (CAD) | |||
6 | A, B | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
7 | A, B | 6-(2-{5-[2-(2-amino-6-methylpyridin-4-yl)ethyl]pyridin-3-yl}ethyl)-4-methylpyridin-2-amine | non-polymer | 347.5 | 2 | Chemie (XFK) | |||
8 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
9 | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence modifications
A, B: 39 - 482 (UniProt: P29473)
PDB | External Database | Details |
---|---|---|
Arg 100 | Cys 100 | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 99420.2 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 3054.1 | |
All* | Total formula weight | 102474.3 |