3N56

Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human B-type natriuretic peptide (BNP)

Summary for 3N56

• Entry DOI: 10.2210/pdb3n56/pdb
• Related: 1YK1 2G47 2WBY 3CWW 3E4Z 3H44 3N57
• Descriptor: Insulin-degrading enzyme, Natriuretic peptides B, ZINC ION, ... (5 entities in total)
• Functional Keywords: insulysin, insulinase, a-beta degrading enzyme, cryptidase, hydrolase, hormone, disease mutation, diabetes mellitus, insulin, cardiac, secreted, protease, disulfide bond, metalloprotease, human insulin-degradng enzyme, metal-binding, natriuretic peptide, natriuretic factor, cardiovascular regulation, hydrolase-hormone complex, hydrolase/hormone
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P14735; Secreted: P16860
• Total number of polymer chains: 4
• Total formula weight: 236376.42

Authors

Funke, T.,Guo, Q.,Tang, W.-J. (deposition date: 2010-05-24, release date: 2010-11-17, Last modification date: 2023-09-06)

• Primary citation: Ralat, L.A.,Funke, T.,Ren, M.,Guo, Q.,Dickey, D.M.,Potter, L.R.,Tang, W.-J.; Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human B-type natriuretic peptide (BNP); To be Published,

Experimental method

X-RAY DIFFRACTION (3.102 Å)