3MZW
HER2 extracelluar region with affinity matured 3-helix affibody ZHER2:342
Summary for 3MZW
Entry DOI | 10.2210/pdb3mzw/pdb |
Descriptor | Tyrosine kinase-type cell surface receptor HER2, Immunoglobulin G-binding protein A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | protein-protein complex, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 76375.46 |
Authors | Eigenbrot, C.,Ultsch, M.H. (deposition date: 2010-05-13, release date: 2010-07-28, Last modification date: 2023-09-06) |
Primary citation | Eigenbrot, C.,Ultsch, M.,Dubnovitsky, A.,Abrahmsen, L.,Hard, T. Structural basis for high-affinity HER2 receptor binding by an engineered protein. Proc.Natl.Acad.Sci.USA, 107:15039-15044, 2010 Cited by PubMed: 20696930DOI: 10.1073/pnas.1005025107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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