3MV7

Crystal Structure of the TK3 TCR in complex with HLA-B*3501/HPVG

3MV7 の概要

• エントリーDOI: 10.2210/pdb3mv7/pdb
• 関連するPDBエントリー: 2fyy 3MV8 3MV9
• 分子名称: HLA class I histocompatibility antigen, B-35 alpha chain, Beta-2-microglobulin, HPVG peptide from Epstein-Barr nuclear antigen 1, ... (7 entities in total)
• 機能のキーワード: hla b*3501, ebv, tcr, tcrpmhc complex, hpvg, tcr polymorphism, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30685; Secreted: P61769; Host nucleus: P03211
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 94478.42

構造登録者

Gras, S.,Chen, Z.,Miles, J.J.,Liu, Y.C.,Bell, M.J.,Sullivan, L.C.,Kjer-Nielsen, L.,Brennan, R.M.,Burrows, J.M.,Neller, M.A.,Khanna, R.,Purcell, A.W.,Brooks, A.G.,McCluskey, J.,Rossjohn, J.,Burrows, S.R. (登録日: 2010-05-03, 公開日: 2010-06-09, 最終更新日: 2011-07-20)

• 主引用文献: Gras, S.,Chen, Z.,Miles, J.J.,Liu, Y.C.,Bell, M.J.,Sullivan, L.C.,Kjer-Nielsen, L.,Brennan, R.M.,Burrows, J.M.,Neller, M.A.,Khanna, R.,Purcell, A.W.,Brooks, A.G.,McCluskey, J.,Rossjohn, J.,Burrows, S.R.; Allelic polymorphism in the T cell receptor and its impact on immune responses; J.Exp.Med., 207:1555-1567, 2010; PubMed: 20566715; DOI: 10.1084/jem.20100603

実験手法

X-RAY DIFFRACTION (2 Å)