3MOR

Crystal structure of Cathepsin B from Trypanosoma Brucei

Summary for 3MOR

• Entry DOI: 10.2210/pdb3mor/pdb
• Related: 1HUC 1QDQ
• Descriptor: Cathepsin B-like cysteine protease, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (6 entities in total)
• Functional Keywords: thiol protease, hydrolase
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 71246.38

Authors

Cupelli, K.,Stehle, T. (deposition date: 2010-04-23, release date: 2011-11-02, Last modification date: 2023-09-06)

• Primary citation: Koopmann, R.,Cupelli, K.,Redecke, L.,Nass, K.,Deponte, D.P.,White, T.A.,Stellato, F.,Rehders, D.,Liang, M.,Andreasson, J.,Aquila, A.,Bajt, S.,Barthelmess, M.,Barty, A.,Bogan, M.J.,Bostedt, C.,Boutet, S.,Bozek, J.D.,Caleman, C.,Coppola, N.,Davidsson, J.,Doak, R.B.,Ekeberg, T.,Epp, S.W.,Erk, B.,Fleckenstein, H.,Foucar, L.,Graafsma, H.,Gumprecht, L.,Hajdu, J.,Hampton, C.Y.,Hartmann, A.,Hartmann, R.,Hauser, G.,Hirsemann, H.,Holl, P.,Hunter, M.S.,Kassemeyer, S.,Kirian, R.A.,Lomb, L.,Maia, F.R.,Kimmel, N.,Martin, A.V.,Messerschmidt, M.,Reich, C.,Rolles, D.,Rudek, B.,Rudenko, A.,Schlichting, I.,Schulz, J.,Seibert, M.M.,Shoeman, R.L.,Sierra, R.G.,Soltau, H.,Stern, S.,Struder, L.,Timneanu, N.,Ullrich, J.,Wang, X.,Weidenspointner, G.,Weierstall, U.,Williams, G.J.,Wunderer, C.B.,Fromme, P.,Spence, J.C.,Stehle, T.,Chapman, H.N.,Betzel, C.,Duszenko, M.; In vivo protein crystallization opens new routes in structural biology.; Nat.Methods, 9:259-262, 2012; PubMed: 22286384; DOI: 10.1038/nmeth.1859

Experimental method

X-RAY DIFFRACTION (2.55 Å)