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3MOR

Crystal structure of Cathepsin B from Trypanosoma Brucei

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
A0005615cellular_componentextracellular space
A0005764cellular_componentlysosome
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0008234molecular_functioncysteine-type peptidase activity
A0010608biological_processpost-transcriptional regulation of gene expression
A0046872molecular_functionmetal ion binding
A0051603biological_processproteolysis involved in protein catabolic process
B0004197molecular_functioncysteine-type endopeptidase activity
B0005615cellular_componentextracellular space
B0005764cellular_componentlysosome
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0008234molecular_functioncysteine-type peptidase activity
B0010608biological_processpost-transcriptional regulation of gene expression
B0046872molecular_functionmetal ion binding
B0051603biological_processproteolysis involved in protein catabolic process
Functional Information from PROSITE/UniProt
site_idPS00139
Number of Residues12
DetailsTHIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QSaCGSCWAvAA
ChainResidueDetails
AGLN116-ALA127

site_idPS00639
Number of Residues11
DetailsTHIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. GGHAVRLVGWG
ChainResidueDetails
AGLY280-GLY290

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PDB entries from 2024-04-24

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