3MNG

wild type human PrxV with DTT bound as a competitive inhibitor

Summary for 3MNG

• Entry DOI: 10.2210/pdb3mng/pdb
• Related: 1H4O 1HD2 1OC3 1URM 2VL2 2VL3
• Descriptor: Peroxiredoxin-5, mitochondrial, (4S,5S)-1,2-DITHIANE-4,5-DIOL, BROMIDE ION, ... (5 entities in total)
• Functional Keywords: peroxiredoxin, peroxidase, prxv, substrate analog, dtt, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion: P30044
• Total number of polymer chains: 1
• Total formula weight: 19300.70

Authors

Hall, A.,Karplus, P.A. (deposition date: 2010-04-21, release date: 2010-08-04, Last modification date: 2023-09-06)

• Primary citation: Hall, A.,Parsonage, D.,Poole, L.B.,Karplus, P.A.; Structural Evidence that Peroxiredoxin Catalytic Power Is Based on Transition-State Stabilization.; J.Mol.Biol., 402:194-209, 2010; PubMed: 20643143; DOI: 10.1016/j.jmb.2010.07.022

Experimental method

X-RAY DIFFRACTION (1.45 Å)