3ML5

Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide

Summary for 3ML5

Entry DOI	10.2210/pdb3ml5/pdb
Descriptor	Carbonic anhydrase 7, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (4 entities in total)
Functional Keywords	protein-inhibitor complex, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (Probable): P43166
Total number of polymer chains	1
Total formula weight	30396.38
Authors	Di Fiore, A.,Truppo, E.,Supuran, C.T.,Alterio, V.,Dathan, N.,Bootorabi, F.,Parkkila, S.,Monti, S.M.,De Simone, G. (deposition date: 2010-04-16, release date: 2011-03-02, Last modification date: 2023-11-01)
Primary citation	Di Fiore, A.,Truppo, E.,Supuran, C.T.,Alterio, V.,Dathan, N.,Bootorabi, F.,Parkkila, S.,Monti, S.M.,De Simone, G. Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide Bioorg.Med.Chem.Lett., 20:5023-5026, 2010 Cited by PubMed: 20688517 DOI: 10.1016/j.bmcl.2010.07.051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation