3MKP

Crystal structure of 1K1 mutant of Hepatocyte Growth Factor/Scatter Factor fragment NK1 in complex with heparin

3MKP の概要

• エントリーDOI: 10.2210/pdb3mkp/pdb
• 関連するPDBエントリー: 1BHT 1GMN 1GMO 1GP9 1NK1
• 分子名称: Hepatocyte growth factor, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: growth factor, supramolecular assembly, hgf/sf, met receptor, nk1, hormone
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 87891.49

構造登録者

Gherardi, E.,Chirgadze, D.Y.,Blundell, T.L. (登録日: 2010-04-15, 公開日: 2010-08-18, 最終更新日: 2023-11-01)

• 主引用文献: Gherardi, E.,Chirgadze, D.Y.,Bocci, M.,Brocchieri, C.,Bevan, D.,Kajstura, J.,Esposito, G.,Lietha, D.,Rota, M.,Leri, A.,Mallorqui-Fernandez, N.,Bandyopadhyay, A.,Youles, M.,Mulloy, B.,Rowe, A.,Alison, M.,Edwards, D.,Vannini, V.,Blundell, T.,Anversa, P.; Engineering a fragment of Hepatocyte Growth Factor/Scatter Factor for tissue and organ regeneration; To be Published,

実験手法

X-RAY DIFFRACTION (2.81 Å)