3MJX

Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin

Summary for 3MJX

Entry DOI	10.2210/pdb3mjx/pdb
Related	1YV3 2JHR 2JJ9 3BZ7 3BZ8 3BZ9
Descriptor	Myosin-2 heavy chain, ADP METAVANADATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	contractile protein, allosteric, methylation, atp-binding, motor protein, actin-binding, phosphoprotein, adp-metavanadate, calmodulin-binding, nucleotide-binding, blebbistatin, myosin, structural protein
Biological source	Dictyostelium discoideum (Slime mold)
Cellular location	Cytoplasm, cell cortex: P08799
Total number of polymer chains	1
Total formula weight	90858.35
Authors	Fedorov, R.,Baruch, P.,Bauer, S.,Manstein, D.J. (deposition date: 2010-04-13, release date: 2011-04-27, Last modification date: 2024-03-13)
Primary citation	Fedorov, R.,Bohl, M.,Tsiavaliaris, G.,Hartmann, F.K.,Taft, M.H.,Baruch, P.,Brenner, B.,Martin, R.,Knolker, H.J.,Gutzeit, H.O.,Manstein, D.J. The mechanism of pentabromopseudilin inhibition of myosin motor activity. Nat.Struct.Mol.Biol., 16:80-88, 2009 Cited by PubMed: 19122661 DOI: 10.1038/nsmb.1542 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation