3MJX

Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Myosin-2 heavy chain	polymer	788	90014.6	1	UniProt (P08799) Pfam (PF02736) Pfam (PF00063) In PDB	Dictyostelium discoideum (Slime mold)	Myosin II heavy chain
2	A	ADP METAVANADATE	non-polymer		527.1	1	Chemie (AD9)		Myosin II heavy chain
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	A	(-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE	non-polymer		292.3	1	Chemie (BIT)
5		water	water		18.0	500	Chemie (HOH)

Sequence modifications

A: 2 - 761 (UniProt: P08799)

PDB	External Database	Details
Met -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Asp -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag
Glu 1	-	expression tag
Leu 762	-	expression tag
Glu 763	-	expression tag
Ser 764	-	expression tag
Asn 765	-	expression tag
Glu 766	-	expression tag
Pro 767	-	expression tag
Pro 768	-	expression tag
Met 769	-	expression tag
Asp 770	-	expression tag
Phe 771	-	expression tag
Asp 772	-	expression tag
Asp 773	-	expression tag
Asp 774	-	expression tag
Ile 775	-	expression tag
Pro 776	-	expression tag
Phe 777	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	90014.6
Non-Polymers*	Number of molecules	3
	Total formula weight	843.8
All*	Total formula weight	90858.3

*Water molecules are not included.