3MJH
Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1
Summary for 3MJH
Entry DOI | 10.2210/pdb3mjh/pdb |
Descriptor | Ras-related protein Rab-5A, Early endosome antigen 1, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | protein-zinc finger complex, beta beta alpha fold, beta hairpin, rab5a gtpase, eea1, protein transport |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P20339 Cytoplasm: Q15075 |
Total number of polymer chains | 4 |
Total formula weight | 46184.69 |
Authors | Mishra, A.K.,Eathiraj, S.,Lambright, D.G. (deposition date: 2010-04-12, release date: 2010-05-05, Last modification date: 2024-02-21) |
Primary citation | Mishra, A.,Eathiraj, S.,Corvera, S.,Lambright, D.G. Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1). Proc.Natl.Acad.Sci.USA, 107:10866-10871, 2010 Cited by PubMed: 20534488DOI: 10.1073/pnas.1000843107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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