3MJH

Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1

3MJH の概要

• エントリーDOI: 10.2210/pdb3mjh/pdb
• 分子名称: Ras-related protein Rab-5A, Early endosome antigen 1, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: protein-zinc finger complex, beta beta alpha fold, beta hairpin, rab5a gtpase, eea1, protein transport
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P20339; Cytoplasm: Q15075
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 46184.69

構造登録者

Mishra, A.K.,Eathiraj, S.,Lambright, D.G. (登録日: 2010-04-12, 公開日: 2010-05-05, 最終更新日: 2024-02-21)

• 主引用文献: Mishra, A.,Eathiraj, S.,Corvera, S.,Lambright, D.G.; Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).; Proc.Natl.Acad.Sci.USA, 107:10866-10871, 2010; PubMed: 20534488; DOI: 10.1073/pnas.1000843107

実験手法

X-RAY DIFFRACTION (2.03 Å)