3MHS

Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde

3MHS の概要

• エントリーDOI: 10.2210/pdb3mhs/pdb
• 関連するPDBエントリー: 3MHH
• 分子名称: Ubiquitin carboxyl-terminal hydrolase 8, Protein SUS1, SAGA-associated factor 11, ... (9 entities in total)
• 機能のキーワード: multi-protein complex, hydrolase-transcription regulator-protein binding complex, acetylation, cytoplasm, isopeptide bond, nucleus, phosphoprotein, ubl conjugation, hydrolase/transcription regulator/protein binding
• 由来する生物種: Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast); 詳細
• 細胞内の位置: Nucleus (Probable): P50102 Q03067 P62988; Nucleus, nucleoplasm: Q6WNK7
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 96488.29

構造登録者

Samara, N.L.,Datta, A.B.,Berndsen, C.E.,Zhang, X.,Yao, T.,Cohen, R.E.,Wolberger, C. (登録日: 2010-04-08, 公開日: 2010-04-21, 最終更新日: 2011-07-13)

• 主引用文献: Samara, N.L.,Datta, A.B.,Berndsen, C.E.,Zhang, X.,Yao, T.,Cohen, R.E.,Wolberger, C.; Structural insights into the assembly and function of the SAGA deubiquitinating module.; Science, 328:1025-1029, 2010; PubMed: 20395473; DOI: 10.1126/science.1190049

実験手法

X-RAY DIFFRACTION (1.89 Å)