3MG0
Structure of yeast 20S proteasome with bortezomib
Summary for 3MG0
Entry DOI | 10.2210/pdb3mg0/pdb |
Related | 3MG4 3MG6 3MG7 3MG8 |
Descriptor | Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (16 entities in total) |
Functional Keywords | 20s proteasome, hydrolase |
Biological source | Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast) More |
Cellular location | Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 |
Total number of polymer chains | 28 |
Total formula weight | 706511.66 |
Authors | Sintchak, M.D. (deposition date: 2010-04-05, release date: 2011-05-18, Last modification date: 2023-09-06) |
Primary citation | Blackburn, C.,Gigstad, K.M.,Hales, P.,Garcia, K.,Jones, M.,Bruzzese, F.J.,Barrett, C.,Liu, J.X.,Soucy, T.A.,Sappal, D.S.,Bump, N.,Olhava, E.J.,Fleming, P.,Dick, L.R.,Tsu, C.,Sintchak, M.D.,Blank, J.L. Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem.J., 430:461-476, 2010 Cited by PubMed: 20632995DOI: 10.1042/BJ20100383 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
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