3MFI
DNA Polymerase Eta in Complex With a cis-syn Thymidine Dimer
Summary for 3MFI
Entry DOI | 10.2210/pdb3mfi/pdb |
Related | 1JIH 3MFH |
Descriptor | DNA polymerase eta, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(*TP*AP*AP*(TTD)P*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ... (7 entities in total) |
Functional Keywords | dna damage, dna repair, dna replication, dna synthesis, nucleus, dna-binding, magnesium, metal-binding, dna-directed dna polymerase, mutator protein, nucleotidyltransferase, dna polymerase eta, protein-dna complex, thymidine dimer, cpd, uv-damage, transferase-dna complex, transferase/dna |
Biological source | Saccharomyces cerevisiae (yeast) More |
Cellular location | Nucleus : Q04049 |
Total number of polymer chains | 3 |
Total formula weight | 67777.70 |
Authors | Silverstein, T.D.,Johnson, R.E.,Jain, R.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2010-04-02, release date: 2010-06-23, Last modification date: 2023-09-06) |
Primary citation | Silverstein, T.D.,Johnson, R.E.,Jain, R.,Prakash, L.,Prakash, S.,Aggarwal, A.K. Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature, 465:1039-1043, 2010 Cited by PubMed: 20577207DOI: 10.1038/nature09104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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