3MFH

DNA Polymerase Eta in Complex With Undamaged DNA

Summary for 3MFH

• Entry DOI: 10.2210/pdb3mfh/pdb
• Related: 1JIH 3MFI
• Descriptor: DNA polymerase eta, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(*TP*AP*AP*TP*TP*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ... (7 entities in total)
• Functional Keywords: dna polymerase eta, dna-directed dna polymerase, dna replication, dna synthesis, dna damage, dna binding, protein-dna complex, magnesium, metal binding, nucleotidyltransferase, thymidine dimer, cpd, uv-damage, dna repair, nucleus, mutator protein, transferase-dna complex, transferase/dna
• Biological source: Saccharomyces cerevisiae (yeast)
• Cellular location: Nucleus : Q04049
• Total number of polymer chains: 3
• Total formula weight: 67777.70

Authors

Silverstein, T.D.,Johnson, R.E.,Jain, R.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2010-04-02, release date: 2010-06-23, Last modification date: 2023-09-06)

• Primary citation: Silverstein, T.D.,Johnson, R.E.,Jain, R.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Structural basis for the suppression of skin cancers by DNA polymerase eta.; Nature, 465:1039-1043, 2010; PubMed: 20577207; DOI: 10.1038/nature09104

Experimental method

X-RAY DIFFRACTION (2 Å)