3MAZ

Crystal Structure of the Human BRDG1/STAP-1 SH2 Domain in Complex with the NTAL pTyr136 Peptide

Summary for 3MAZ

Entry DOI	10.2210/pdb3maz/pdb
Descriptor	Signal-transducing adaptor protein 1, CheD family protein, MALONATE ION, ... (4 entities in total)
Functional Keywords	modular domain, phosphotyrosine, specificity, cytoplasm, phosphoprotein, sh2 domain, signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm (Potential): Q9ULZ2 Cell membrane; Single-pass type III membrane protein: Q9GZY6
Total number of polymer chains	2
Total formula weight	15582.51
Authors	Kaneko, T.,Huang, H.,Zhao, B.,Li, L.,Liu, H.,Voss, C.K.,Wu, C.,Schiller, M.R.,Li, S.S. (deposition date: 2010-03-24, release date: 2010-05-12, Last modification date: 2023-11-22)
Primary citation	Kaneko, T.,Huang, H.,Zhao, B.,Li, L.,Liu, H.,Voss, C.K.,Wu, C.,Schiller, M.R.,Li, S.S. Loops govern SH2 domain specificity by controlling access to binding pockets. Sci.Signal., 3:ra34-ra34, 2010 Cited by PubMed: 20442417 DOI: 10.1126/scisignal.2000796 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation