3LV2
Crystal structure of Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase in complex with substrate analog sinefungin
Summary for 3LV2
Entry DOI | 10.2210/pdb3lv2/pdb |
Related | 3BV0 |
Descriptor | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SINEFUNGIN, ... (4 entities in total) |
Functional Keywords | rv1568, aminotransferase, bioa, 7, 8-diaminopelargonic acid synthase, biotin biosynthesis, pyridoxal phosphate, s-adenosyl-l-methionine, transferase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm (By similarity): P0A4X6 |
Total number of polymer chains | 2 |
Total formula weight | 99328.09 |
Authors | Dey, S.,Sacchettini, J.C. (deposition date: 2010-02-19, release date: 2010-08-25, Last modification date: 2023-09-06) |
Primary citation | Dey, S.,Lane, J.M.,Lee, R.E.,Rubin, E.J.,Sacchettini, J.C. Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49:6746-6760, 2010 Cited by PubMed: 20565114DOI: 10.1021/bi902097j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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