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3LV2

Crystal structure of Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase in complex with substrate analog sinefungin

Summary for 3LV2
Entry DOI10.2210/pdb3lv2/pdb
Related3BV0
DescriptorAdenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SINEFUNGIN, ... (4 entities in total)
Functional Keywordsrv1568, aminotransferase, bioa, 7, 8-diaminopelargonic acid synthase, biotin biosynthesis, pyridoxal phosphate, s-adenosyl-l-methionine, transferase
Biological sourceMycobacterium tuberculosis
Cellular locationCytoplasm (By similarity): P0A4X6
Total number of polymer chains2
Total formula weight99328.09
Authors
Dey, S.,Sacchettini, J.C. (deposition date: 2010-02-19, release date: 2010-08-25, Last modification date: 2023-09-06)
Primary citationDey, S.,Lane, J.M.,Lee, R.E.,Rubin, E.J.,Sacchettini, J.C.
Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase .
Biochemistry, 49:6746-6760, 2010
Cited by
PubMed: 20565114
DOI: 10.1021/bi902097j
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.18 Å)
Structure validation

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