3LUG
Crystal structure of MID domain from hAGO2 in complex with CMP
Summary for 3LUG
Entry DOI | 10.2210/pdb3lug/pdb |
Related | 3luc 3lud 3luh 3luj 3luk |
Descriptor | Protein argonaute-2, PHOSPHATE ION, CYTIDINE-5'-MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | mid domain, ribonucleoprotein, rna-binding, rna-mediated gene silencing, translation regulation, rna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 47422.31 |
Authors | Frank, F.,Sonenberg, N.,Nagar, B. (deposition date: 2010-02-17, release date: 2010-05-26, Last modification date: 2024-02-21) |
Primary citation | Frank, F.,Sonenberg, N.,Nagar, B. Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature, 465:818-822, 2010 Cited by PubMed: 20505670DOI: 10.1038/nature09039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.849 Å) |
Structure validation
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