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3LUG

Crystal structure of MID domain from hAGO2 in complex with CMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Protein argonaute-2polymer13815326.03UniProt (Q9UKV8)
Pfam (PF16487)
Homo sapiens (human)Argonaute2, hAgo2, Protein slicer, PAZ Piwi domain protein, PPD, Eukaryotic translation initiation factor 2C 2, eIF-2C 2, eIF2C 2
2D, G, H, I, J
(A, B, C)
PHOSPHATE IONnon-polymer95.05Chemie (PO4)
3E, F, K
(A, B, C)
CYTIDINE-5'-MONOPHOSPHATEnon-polymer323.23Chemie (C5P)
4L, M, N
(A, B, C)
waterwater18.0387Chemie (HOH)
Sequence modifications
A, B, C: 439 - 575 (UniProt: Q9UKV8)
PDBExternal DatabaseDetails
Ser 438-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight45977.9
Non-Polymers*Number of molecules8
Total formula weight1444.4
All*Total formula weight47422.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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