3LRL

Structure of alfa-galactosidase (MEL1) from Saccharomyces cerevisiae with melibiose

Summary for 3LRL

• Entry DOI: 10.2210/pdb3lrl/pdb
• Related: 3LRK 3LRM
• Related PRD ID: PRD_900037
• Descriptor: Alpha-galactosidase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: alpha-galactosidase, tetramer, gh27, melibiose, glycoprotein, glycosidase, hydrolase
• Biological source: Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
• Cellular location: Secreted: P04824
• Total number of polymer chains: 1
• Total formula weight: 55226.55

Authors

Fernandez-Leiro, R.,Pereira-Rodriguez, A.,Cerdan, M.E.,Becerra, M.,Sanz-Aparicio, J. (deposition date: 2010-02-11, release date: 2010-06-30, Last modification date: 2023-09-06)

• Primary citation: Fernandez-Leiro, R.,Pereira-Rodriguez, A.,Cerdan, M.E.,Becerra, M.,Sanz-Aparicio, J.; Structural analysis of Saccharomyces cerevisiae alpha-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases.; J.Biol.Chem., 285:28020-28033, 2010; PubMed: 20592022; DOI: 10.1074/jbc.M110.144584

Experimental method

X-RAY DIFFRACTION (2.4 Å)