3LL2
Monomeric Griffithsin in Complex with a High-Mannose Branched Carbohydrate
Summary for 3LL2
Entry DOI | 10.2210/pdb3ll2/pdb |
Related | 2gty 2guc 2gud 2gue 2gux 2hyq 2hyr 2nu5 2nuo 3LKY 3LL0 3LL1 |
Descriptor | Griffithsin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | lectin, sugar-binding, anti-hiv, high mannose, man9, gp120, gp41, jacalin-related, mannose-binding, sugar binding protein |
Biological source | Griffithsia (Red alga) |
Total number of polymer chains | 1 |
Total formula weight | 14674.59 |
Authors | Moulaei, T.,Wlodawer, A. (deposition date: 2010-01-28, release date: 2010-10-06, Last modification date: 2023-09-06) |
Primary citation | Moulaei, T.,Shenoy, S.R.,Giomarelli, B.,Thomas, C.,McMahon, J.B.,Dauter, Z.,O'Keefe, B.R.,Wlodawer, A. Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity. Structure, 18:1104-1115, 2010 Cited by PubMed: 20826337DOI: 10.1016/j.str.2010.05.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.97 Å) |
Structure validation
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