2HYQ

Crystal structure of a complex of griffithsin with 6alpha-mannobiose

Summary for 2HYQ

Entry DOI	10.2210/pdb2hyq/pdb
Related	2GTY 2GUC 2GUD 2GUE 2GUX 2HYR
Related PRD ID	PRD_900118
Descriptor	Griffithsin, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, SULFATE ION, ... (4 entities in total)
Functional Keywords	griffithsin, lectins, domain swapping, mannose binding, hiv, sars, sugar binding protein
Biological source	Griffithsia
Total number of polymer chains	2
Total formula weight	27795.65
Authors	Ziolkowska, N.E.,Wlodawer, A. (deposition date: 2006-08-07, release date: 2007-04-24, Last modification date: 2023-08-30)
Primary citation	Ziolkowska, N.E.,Shenoy, S.R.,O'keefe, B.R.,McMahon, J.B.,Palmer, K.E.,Dwek, R.A.,Wormald, M.R.,Wlodawer, A. Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin. Proteins, 67:661-670, 2007 Cited by PubMed: 17340634 DOI: 10.1002/prot.21336 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation