3LKZ

Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase

Summary for 3LKZ

Related2OY0
DescriptorNon-structural protein 5, SINEFUNGIN, GLYCEROL, ... (4 entities in total)
Functional Keywordswest nile virus, flavivirus, methyltransferase, inhibitor, pocket, nucleotide-binding, rna replication, viral protein
Biological sourceWest Nile virus (WNV)
Cellular locationEnvelope protein E: Virion membrane; Multi- pass membrane protein Q9Q6P4
Total number of polymer chains2
Total molecular weight74432.59
Authors
Liu, L.H.,Li, H.M. (deposition date: 2010-01-28, release date: 2010-08-04, Last modification date: 2011-07-13)
Primary citation
Dong, H.,Liu, L.,Zou, G.,Zhao, Y.,Li, Z.,Lim, S.P.,Shi, P.Y.,Li, H.
Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase.
J.Biol.Chem., 285:32586-32595, 2010
PubMed: 20685660 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.129197
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.267210.8%4.9%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3lkz
no rotation
Molmil generated image of 3lkz
rotated about x axis by 90°
Molmil generated image of 3lkz
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 3lkz
no rotation
Molmil generated image of 3lkz
rotated about x axis by 90°
Molmil generated image of 3lkz
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3lkz.pdb2.gz [50.55 KB])
Coordinate files for Biological unit (3lkz.pdb1.gz [48.98 KB])
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan