3LDW

Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound

3LDW の概要

• エントリーDOI: 10.2210/pdb3ldw/pdb
• 分子名称: Farnesyl pyrophosphate synthase, ZOLEDRONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: malaria, farnesyl pyrophosphate synthase diphosphate, lyase, structural genomics, isoprene biosynthesis, transferase, structural genomics consortium, sgc
• 由来する生物種: Plasmodium vivax
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 187627.81

構造登録者

Wernimont, A.K.,Lew, J.,Zhao, Y.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Bochkarev, A.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Hui, R.,Artz, J.D.,Structural Genomics Consortium (SGC) (登録日: 2010-01-13, 公開日: 2010-11-17, 最終更新日: 2024-02-21)

• 主引用文献: Artz, J.D.,Wernimont, A.K.,Dunford, J.E.,Schapira, M.,Dong, A.,Zhao, Y.,Lew, J.,Russell, R.G.,Ebetino, F.H.,Oppermann, U.,Hui, R.; Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.; J.Biol.Chem., 286:3315-3322, 2011; PubMed: 21084289; DOI: 10.1074/jbc.M109.027235

実験手法

X-RAY DIFFRACTION (2.47 Å)